George Anderson, PhD

  • Senior Research Scientist in the Child Study Center and in Laboratory Medicine
  • Director, Core Resource Laboratory of the Yale Interdisciplinary Research Consortium on Stress, Self-Control and Addiction
  • Director, Laboratory of Developmental Neurochemistry (Child Study Center)
Dr. Anderson has a record of extensive collaboration with investigators at Yale University, a large number of national and international collaborations, and has authored or co-authored of over 250 publications in the fields of biological psychiatry, psychopharmacology and analytical chemistry.

He has served on the scientific advisory boards of Cure Autism Now and Autism Speaks, and presently serves on the editorial boards of Autism Research and the Journal of Autism and Developmental Disorders.
Research interests
Autistic Disorder; Canada; Child Psychiatry; Depression; Tourette Syndrome; Netherlands; Neurobiology; Stress Disorders, Post-Traumatic; Attention Deficit and Disruptive Behavior Disorders; Neuropsychiatry
Research summary

Research includes studies on the neurobiology of childhood neuropsychiatric disorders including autism, Tourette syndrome and ADHD, as well as adult depression, PTSD and addiction.

Specialized Terms: Stress response systems; Serotonin neurochemistry and psychopharmacology; Early biomarkers

Education
  • PhD, McGill University, 1978
Publications
  • Anderson GM. The potential role for emergence in autism. Autism Research, 1:18-30, 2008.
  • Anderson GM, Scahill L, McCracken JT, et al. Effects of short- and long-term risperidone treatment on prolactin levels in children with autism.Biological Psychiatry, 61:545-50, 2007.
  • Anderson GM, Jacobs-Stannard A, Chawarska K, Volkmar FR, Kliman HJ. Placental Trophoblast Inclusions in Autism Spectrum Disorder. Biological Psychiatry, 61:487-91, 2007.
  • Tordjman S, Anderson GM, Pichard N, et al. Nocturnal excretion of 6-sulphatoxymelatonin in children and adolescents with autistic disorder. Biological Psychiatry. 57:134-8, 2005
  • Anderson GM, Barr CS, Lindell S, Durham AC, Shifrovich I, Higley JD. Time course of the effects of the serotonin-selective reuptake inhibitor sertraline on central and peripheral serotonin neurochemistry in the rhesus monkey. Psychopharmacology. 178:339-46, 2005.
International activities
  • Neurochemical Research
    Canada (2008-Present)
    Dr. Anderson engages in neurochemical collaborations with faculty at McGill University.

    McGill University, McGill University

  • Autism Research
    Netherlands, Netherlands (2003-Present)
    Dr. Anderson engages in autism research collaboration with child psychiatrists at the Universities of Groningen and Utrecht. The research is supported by the Amsterdam-based Korczak Foundation for Autism Research.

    University of Groningen, University of Groningen, Utrecht University, Utrecht University

  • Autism Research
    France, France (2003-Present)
    Dr. Anderson engages in longstanding and ongoing autism research collaboration with child psychiatrists and geneticists associated withe University of Paris and INSERM.

    Inst Natl dl Sante & dl Recherche Med, Inst Natl dl Sante & dl Recherche Med, Univ of Paris, Univ of Paris

  • Suicidal behavior
    Israel (2003-Present)
    Dr. Anderson engages in ongoing research collaboration with child psychiatrists at Tel Aviv University studying the biological basis of suicidal behavior.

    Tel Aviv University , Tel Aviv University

Current projects
Research includes studies on the neurobiology of childhood neuropsychiatric disorders including autism, Tourette syndrome and ADHD, as well as adult depression, PTSD and addiction.

In a large Dutch collaborative study, we have demonstrated bimodal distribution of platelet serotonin in autism. Follow-up studies are attempting to identify disorder- and subgroup-specific alterations of potential etiological significance. Possible neurochemical (catecholamines) and neuroendocrine predictors and surrogates of treatment response in autism are being examined in multi-center studies coordinated by Dr. Lawrence Scahill of the Yale Child Study Center. In collaboration with Dr. Sylvie Tordjman of the University of Rennes, we are examining pineal function and sleep problems in autism, as well as investigating the relationship of ß-endorphin, pain reactivity and self-injurious behavior in autism.

Collaborative studies with three primate facilities have examined the ontogeny of neurotransmitter systems in rhesus monkeys and chimpanzee, neurochemical-behavioral correlates, and the effects of the short- and long-term SSRI in adolescent and adult rhesus. A series of collaborative human studies examine hypothalamic-pituitary-adrenal (HPA) axis and sympathoadrenomedullary functioning in ADHD, Tourette syndrome, PTSD, smoking behavior, substance abuse, depression and trauma.