George Anderson, PhD
- Senior Research Scientist in the Child Study Center and in Laboratory Medicine
- Director, Core Resource Laboratory of the Yale Interdisciplinary Research Consortium on Stress, Self-Control and Addiction
- Director, Laboratory of Developmental Neurochemistry (Child Study Center)
He has served on the scientific advisory boards of Cure Autism Now and Autism Speaks, and presently serves on the editorial boards of Autism Research and the Journal of Autism and Developmental Disorders.
Research includes studies on the neurobiology of childhood neuropsychiatric disorders including autism, Tourette syndrome and ADHD, as well as adult depression, PTSD and addiction.
Specialized Terms: Stress response systems; Serotonin neurochemistry and psychopharmacology; Early biomarkers
- PhD, McGill University, 1978
- Anderson GM. The potential role for emergence in autism. Autism Research, 1:18-30, 2008.
- Anderson GM, Scahill L, McCracken JT, et al. Effects of short- and long-term risperidone treatment on prolactin levels in children with autism.Biological Psychiatry, 61:545-50, 2007.
- Anderson GM, Jacobs-Stannard A, Chawarska K, Volkmar FR, Kliman HJ. Placental Trophoblast Inclusions in Autism Spectrum Disorder. Biological Psychiatry, 61:487-91, 2007.
- Tordjman S, Anderson GM, Pichard N, et al. Nocturnal excretion of 6-sulphatoxymelatonin in children and adolescents with autistic disorder. Biological Psychiatry. 57:134-8, 2005
- Anderson GM, Barr CS, Lindell S, Durham AC, Shifrovich I, Higley JD. Time course of the effects of the serotonin-selective reuptake inhibitor sertraline on central and peripheral serotonin neurochemistry in the rhesus monkey. Psychopharmacology. 178:339-46, 2005.
- Neurochemical Research
Dr. Anderson engages in neurochemical collaborations with faculty at McGill University.
McGill University, McGill University
- Autism Research
Netherlands, Netherlands (2003-Present)
Dr. Anderson engages in autism research collaboration with child psychiatrists at the Universities of Groningen and Utrecht. The research is supported by the Amsterdam-based Korczak Foundation for Autism Research.
University of Groningen, University of Groningen, Utrecht University, Utrecht University
- Autism Research
France, France (2003-Present)
Dr. Anderson engages in longstanding and ongoing autism research collaboration with child psychiatrists and geneticists associated withe University of Paris and INSERM.
Inst Natl dl Sante & dl Recherche Med, Inst Natl dl Sante & dl Recherche Med, Univ of Paris, Univ of Paris
- Suicidal behavior
Dr. Anderson engages in ongoing research collaboration with child psychiatrists at Tel Aviv University studying the biological basis of suicidal behavior.
Tel Aviv University , Tel Aviv University
In a large Dutch collaborative study, we have demonstrated bimodal distribution of platelet serotonin in autism. Follow-up studies are attempting to identify disorder- and subgroup-specific alterations of potential etiological significance. Possible neurochemical (catecholamines) and neuroendocrine predictors and surrogates of treatment response in autism are being examined in multi-center studies coordinated by Dr. Lawrence Scahill of the Yale Child Study Center. In collaboration with Dr. Sylvie Tordjman of the University of Rennes, we are examining pineal function and sleep problems in autism, as well as investigating the relationship of ß-endorphin, pain reactivity and self-injurious behavior in autism.
Collaborative studies with three primate facilities have examined the ontogeny of neurotransmitter systems in rhesus monkeys and chimpanzee, neurochemical-behavioral correlates, and the effects of the short- and long-term SSRI in adolescent and adult rhesus. A series of collaborative human studies examine hypothalamic-pituitary-adrenal (HPA) axis and sympathoadrenomedullary functioning in ADHD, Tourette syndrome, PTSD, smoking behavior, substance abuse, depression and trauma.